3MLX

Crystal structure of anti-HIV-1 V3 Fab 3074 in complex with an MN V3 peptide

3MLX の概要

• エントリーDOI: 10.2210/pdb3mlx/pdb
• 関連するPDBエントリー: 3MLR 3MLS 3MLT 3MLU 3MLV 3MLW 3MLY 3MLZ
• 分子名称: Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab light chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab heavy chain, HIV-1 gp120 third variable region (V3) crown, ... (4 entities in total)
• 機能のキーワード: human monoclonal antibody, fab, hiv-1, gp120, third variable loop, antibody-antigen interaction, immune system
• 由来する生物種: Homo sapiens; 詳細
• 細胞内の位置: Surface protein gp120: Virion membrane ; Peripheral membrane protein . Transmembrane protein gp41: Virion membrane ; Single-pass type I membrane protein : P05877
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 98581.92

構造登録者

Kong, X.-P. (登録日: 2010-04-18, 公開日: 2010-07-14, 最終更新日: 2017-11-08)

• 主引用文献: Jiang, X.,Burke, V.,Totrov, M.,Williams, C.,Cardozo, T.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P.; Conserved structural elements in the V3 crown of HIV-1 gp120.; Nat.Struct.Mol.Biol., 17:955-961, 2010; PubMed: 20622876; DOI: 10.1038/nsmb.1861

実験手法

X-RAY DIFFRACTION (1.9 Å)