3MIE

Oxidized (Cu2+) peptidylglycine alpha-hydroxylating monooxygenase (PHM) with bound azide obtained by soaking (50mM NaN3)

3MIE の概要

• エントリーDOI: 10.2210/pdb3mie/pdb
• 関連するPDBエントリー: 1PHM 3MIB 3MIC 3MID 3MIE 3MIF 3MIG 3MIH 3MLJ 3MLK 3MLL
• 分子名称: Peptidyl-glycine alpha-amidating monooxygenase, COPPER (II) ION, NICKEL (II) ION, ... (7 entities in total)
• 機能のキーワード: oxidoreductase, monooxygenase, bioactive peptide activation, ascorbate
• 由来する生物種: Rattus norvegicus (rat)
• 細胞内の位置: Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein: P14925
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35619.25

構造登録者

Chufan, E.E.,Eipper, B.A.,Mains, R.E.,Amzel, L.M. (登録日: 2010-04-10, 公開日: 2010-11-24, 最終更新日: 2023-09-06)

• 主引用文献: Chufan, E.E.,Prigge, S.T.,Siebert, X.,Eipper, B.A.,Mains, R.E.,Amzel, L.M.; Differential Reactivity Between the Two Copper Sites of Peptidylglycine alpha-Hydroxylating Monooxygenase (PHM); J.Am.Chem.Soc., 132:15565-15572, 2010; PubMed: 20958070; DOI: 10.1021/ja103117r

実験手法

X-RAY DIFFRACTION (3.26 Å)