3MG4

Structure of yeast 20S proteasome with Compound 1

3MG4 の概要

• エントリーDOI: 10.2210/pdb3mg4/pdb
• 関連するPDBエントリー: 3MG0 3MG6 3MG7 3MG8
• 分子名称: Proteasome component Y7, Proteasome component C11, Proteasome component PRE2, ... (17 entities in total)
• 機能のキーワード: 20s proteasome, hydrolase
• 由来する生物種: Saccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast); 詳細
• 細胞内の位置: Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451
• タンパク質・核酸の鎖数: 28
• 化学式量合計: 706049.33

構造登録者

Sintchak, M.D. (登録日: 2010-04-05, 公開日: 2011-04-27, 最終更新日: 2023-09-06)

• 主引用文献: Blackburn, C.,Gigstad, K.M.,Hales, P.,Garcia, K.,Jones, M.,Bruzzese, F.J.,Barrett, C.,Liu, J.X.,Soucy, T.A.,Sappal, D.S.,Bump, N.,Olhava, E.J.,Fleming, P.,Dick, L.R.,Tsu, C.,Sintchak, M.D.,Blank, J.L.; Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit.; Biochem.J., 430:461-476, 2010; PubMed: 20632995; DOI: 10.1042/BJ20100383

実験手法

X-RAY DIFFRACTION (3.11 Å)