3MFE
Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant with H0 movement
Summary for 3MFE
Entry DOI | 10.2210/pdb3mfe/pdb |
Related | 3FHA |
Descriptor | Proteasome subunit beta, Proteasome subunit alpha, ... (4 entities in total) |
Functional Keywords | catalytic domain, hydrogen bonding, mycobacterium tuberculosis, oxazolidinones, protease inhibitors, proteasome endopeptidase complex, protein carbonylation, protein conformation, protein subunits, substrate specificity, thiazoles, helix movement, hydrolase |
Biological source | Mycobacterium tuberculosis More |
Cellular location | Cytoplasm (By similarity): O33245 O33245 O33244 |
Total number of polymer chains | 28 |
Total formula weight | 717759.27 |
Authors | |
Primary citation | Li, D.,Li, H.,Wang, T.,Pan, H.,Lin, G.,Li, H. Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome. Embo J., 2010 Cited by PubMed: 20461058DOI: 10.1038/emboj.2010.95 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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