3MFE

Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant with H0 movement

Summary for 3MFE

Entry DOI	10.2210/pdb3mfe/pdb
Related	3FHA
Descriptor	Proteasome subunit beta, Proteasome subunit alpha, ... (4 entities in total)
Functional Keywords	catalytic domain, hydrogen bonding, mycobacterium tuberculosis, oxazolidinones, protease inhibitors, proteasome endopeptidase complex, protein carbonylation, protein conformation, protein subunits, substrate specificity, thiazoles, helix movement, hydrolase
Biological source	Mycobacterium tuberculosis More
Cellular location	Cytoplasm (By similarity): O33245 O33245 O33244
Total number of polymer chains	28
Total formula weight	717759.27
Authors	Li, D.,Li, H. (deposition date: 2010-04-02, release date: 2010-06-23, Last modification date: 2023-11-22)
Primary citation	Li, D.,Li, H.,Wang, T.,Pan, H.,Lin, G.,Li, H. Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome. Embo J., 2010 Cited by PubMed: 20461058 DOI: 10.1038/emboj.2010.95 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation