3MEK

Crystal Structure of Human Histone-Lysine N-methyltransferase SMYD3 in Complex with S-adenosyl-L-methionine

3MEK の概要

• エントリーDOI: 10.2210/pdb3mek/pdb
• 分子名称: SET and MYND domain-containing protein 3, ZINC ION, S-ADENOSYLMETHIONINE, ... (4 entities in total)
• 機能のキーワード: histone methyltransferase, set and mynd domain-containing protein 3, zinc finger mynd domain-containing protein 1, histone h3, di-methylation, tri-methylation, transcriptional activation, dna-binding, mynd-type zinc finger, set domain, chromatin modification, alternative splicing, chromatin regulator, cytoplasm, metal-binding, methyltransferase, nucleus, s-adenosyl-l-methionine, transferase, zinc, zinc-finger, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm : Q9H7B4
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 50580.16

構造登録者

Lam, R.,Dombrovski, L.,Li, Y.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Wu, H.,Structural Genomics Consortium (SGC) (登録日: 2010-03-31, 公開日: 2010-04-14, 最終更新日: 2017-11-08)

• 主引用文献: Lam, R.,Dombrovski, L.,Li, Y.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Wu, H.; Crystal Structure of Human Histone-Lysine N-methyltransferase SMYD3 in Complex with S-adenosyl-L-methionine; To be Published,

実験手法

X-RAY DIFFRACTION (2.1 Å)