3MCT

VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M3CYT AND S-ADENOSYLHOMOCYSTEINE

Summary for 3MCT

Entry DOI	10.2210/pdb3mct/pdb
Descriptor	VP39, S-ADENOSYL-L-HOMOCYSTEINE, 3-METHYLCYTOSINE, ... (4 entities in total)
Functional Keywords	methylated cytosine, methyltransferase, rna cap analog, poly(a) polymerase, vaccinia, mrna processing, transcription, complex (transferase-rna cap analog)
Biological source	Vaccinia virus
Total number of polymer chains	1
Total formula weight	35329.84
Authors	Hu, G.,Gershon, P.D.,Hodel, A.E.,Quiocho, F.A. (deposition date: 1999-01-05, release date: 1999-07-22, Last modification date: 2024-02-21)
Primary citation	Hu, G.,Gershon, P.D.,Hodel, A.E.,Quiocho, F.A. mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc.Natl.Acad.Sci.USA, 96:7149-7154, 1999 Cited by PubMed: 10377383 DOI: 10.1073/pnas.96.13.7149 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation