3MAM
A molecular switch changes the low to the high affinity state in the substrate binding protein AfProX
Summary for 3MAM
| Entry DOI | 10.2210/pdb3mam/pdb |
| Related | 1SW2 1SW5 |
| Descriptor | Osmoprotection protein (ProX), TRIMETHYL GLYCINE, 1,2-ETHANEDIOL, ... (5 entities in total) |
| Functional Keywords | glycine betaine, binding protein, osmosensing, osmose, thermophilic, archaeon, transport protein |
| Biological source | Archaeoglobus fulgidus |
| Total number of polymer chains | 1 |
| Total formula weight | 31380.73 |
| Authors | Tschapek, B.,Pittelkow, M.,Bremer, E.,Schmitt, L.,Smits, S.H. (deposition date: 2010-03-24, release date: 2011-04-06, Last modification date: 2023-11-15) |
| Primary citation | Tschapek, B.,Pittelkow, M.,Sohn-Bosser, L.,Holtmann, G.,Smits, S.H.,Gohlke, H.,Bremer, E.,Schmitt, L. Arg149 Is Involved in Switching the Low Affinity, Open State of the Binding Protein AfProX into Its High Affinity, Closed State. J.Mol.Biol., 411:36-52, 2011 Cited by PubMed: 21664363DOI: 10.1016/j.jmb.2011.05.039 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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