3MAM

A molecular switch changes the low to the high affinity state in the substrate binding protein AfProX

3MAM の概要

• エントリーDOI: 10.2210/pdb3mam/pdb
• 関連するPDBエントリー: 1SW2 1SW5
• 分子名称: Osmoprotection protein (ProX), TRIMETHYL GLYCINE, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: glycine betaine, binding protein, osmosensing, osmose, thermophilic, archaeon, transport protein
• 由来する生物種: Archaeoglobus fulgidus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 31380.73

構造登録者

Tschapek, B.,Pittelkow, M.,Bremer, E.,Schmitt, L.,Smits, S.H. (登録日: 2010-03-24, 公開日: 2011-04-06, 最終更新日: 2023-11-15)

• 主引用文献: Tschapek, B.,Pittelkow, M.,Sohn-Bosser, L.,Holtmann, G.,Smits, S.H.,Gohlke, H.,Bremer, E.,Schmitt, L.; Arg149 Is Involved in Switching the Low Affinity, Open State of the Binding Protein AfProX into Its High Affinity, Closed State.; J.Mol.Biol., 411:36-52, 2011; PubMed: 21664363; DOI: 10.1016/j.jmb.2011.05.039

実験手法

X-RAY DIFFRACTION (1.8 Å)