3M9M
Crystal Structure of Dpo4 in complex with DNA containing the major cisplatin lesion
Summary for 3M9M
Entry DOI | 10.2210/pdb3m9m/pdb |
Related | 3M9N 3M9O |
Descriptor | DNA polymerase IV, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*AP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*TP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... (8 entities in total) |
Functional Keywords | dpo4, translesion dna synthesis, tls, cisplatin, y-family dna polymerase, protein-dna complex, dna, dna damage, dna repair, dna replication, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, transferase, transferase-dna complex, transferase/dna |
Biological source | Sulfolobus solfataricus More |
Cellular location | Cytoplasm : Q97W02 |
Total number of polymer chains | 3 |
Total formula weight | 50977.83 |
Authors | Wong, J.H.Y.,Ling, H. (deposition date: 2010-03-22, release date: 2010-06-16, Last modification date: 2024-03-13) |
Primary citation | Wong, J.H.,Brown, J.A.,Suo, Z.,Blum, P.,Nohmi, T.,Ling, H. Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. Embo J., 29:2059-2069, 2010 Cited by PubMed: 20512114DOI: 10.1038/emboj.2010.101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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