3M7Q

Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean sea anemone stichodactyla helianthus in complex with bovine pancreatic trypsin

3M7Q の概要

• エントリーDOI: 10.2210/pdb3m7q/pdb
• 分子名称: Cationic trypsin, Kunitz-type proteinase inhibitor SHPI-1, PHOSPHATE ION, ... (4 entities in total)
• 機能のキーワード: trypsin-inhibitor complex, kunitz-type serine-protease inhibitor, digestion, disulfide bond, hydrolase, metal-binding, protease, secreted, serine protease, zymogen, nematocyst, protease inhibitor, serine protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Stichodactyla helianthus (Carribean sea anemone); 詳細
• 細胞内の位置: Secreted, extracellular space: P00760; Secreted: P31713
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30114.84

構造登録者

Garcia-Fernandez, R.,Redecke, L.,Pons, T.,Perbandt, M.,Gil, D.,Talavera, A.,Gonzalez, Y.,de los angeles Chavez, M.,Betzel, C. (登録日: 2010-03-17, 公開日: 2011-03-16, 最終更新日: 2023-09-06)

• 主引用文献: Garcia-Fernandez, R.,Pons, T.,Perbandt, M.,Valiente, P.A.,Talavera, A.,Gonzalez-Gonzalez, Y.,Rehders, D.,Chavez, M.A.,Betzel, C.,Redecke, L.; Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor.; J.Struct.Biol., 180:271-279, 2012; PubMed: 22975140; DOI: 10.1016/j.jsb.2012.08.009

実験手法

X-RAY DIFFRACTION (1.7 Å)