3M6S

Crystal structure of H1N1pdm Hemagglutinin

3M6S の概要

• エントリーDOI: 10.2210/pdb3m6s/pdb
• 分子名称: Hemagglutinin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: influenza virus, hemagglutinin, pandemic, envelope protein, fusion protein, host cell membrane, host membrane, membrane, transmembrane, virion, viral protein
• 由来する生物種: Influenza A virus (A/Darwin/2001/2009(H1N1)); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 347690.97

構造登録者

Yang, H.,Carney, P.J.,Stevens, J. (登録日: 2010-03-16, 公開日: 2010-03-31, 最終更新日: 2024-11-27)

主引用文献

Yang, H.,Carney, P.,Stevens, J.
Structure and Receptor binding properties of a pandemic H1N1 virus hemagglutinin
PLoS Curr, :RRN1152-RRN1152, 2010

PubMed Abstract: The 3D-structure of the major surface viral antigen from the recent H1N1 pandemic influenza virus (A/Darwin/2001/2009) was determined to 2.8 Å resolution. The structure was used to analyze changes in the HA that have emerged during the first 11 months of the pandemic and have raised public health concerns. Receptor binding properties of this protein reveals a strict preference for human-type receptors.

PubMed: 20352039

実験手法

X-RAY DIFFRACTION (2.8 Å)