3M55

SET7/9 Y305F in complex with TAF10-K189me1 peptide and AdoHcy

3M55 の概要

• エントリーDOI: 10.2210/pdb3m55/pdb
• 関連するPDBエントリー: 2F69 3M53 3M54 3M56 3M57 3M58 3M59 3M5A
• 分子名称: Histone-lysine N-methyltransferase SETD7, TAF10 peptide, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• 機能のキーワード: ternary complex, set domain, methyltransferase, s-adenosyl-l-homocysteine, taf10 peptide, n-monomethyllysine, chromatin regulator, chromosomal protein, nucleus, s-adenosyl-l-methionine, transcription, transcription regulation, transferase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: Q8WTS6
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30680.23

構造登録者

Del Rizzo, P.A.,Couture, J.-F.,Roiko, M.S.,Strunk, B.S.,Brunzelle, J.S.,Dirk, L.M.,Houtz, R.L.,Trievel, R.C. (登録日: 2010-03-12, 公開日: 2010-07-28, 最終更新日: 2023-09-06)

• 主引用文献: Del Rizzo, P.A.,Couture, J.F.,Dirk, L.M.,Strunk, B.S.,Roiko, M.S.,Brunzelle, J.S.,Houtz, R.L.,Trievel, R.C.; SET7/9 catalytic mutants reveal the role of active site water molecules in lysine multiple methylation.; J.Biol.Chem., 285:31849-31858, 2010; PubMed: 20675860; DOI: 10.1074/jbc.M110.114587

実験手法

X-RAY DIFFRACTION (1.55 Å)