3M3Y
RNA polymerase II elongation complex C
Summary for 3M3Y
Entry DOI | 10.2210/pdb3m3y/pdb |
Related | 1R9T 1SFO 2E2H 3CO3 3M4O |
Descriptor | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC4, RNA (5'-R(*AP*UP*GP*GP*AP*GP*AP*GP*GP*AP*C)-3'), ... (16 entities in total) |
Functional Keywords | transcription, mrna, multiprotein complex, molecular machine, dna, dna damage, cancer, platinum drug, dna-binding, dna-directed rna polymerase, isopeptide bond, magnesium, metal-binding, nucleotidyltransferase, nucleus, phosphoprotein, transferase, ubl conjugation, zinc, zinc-finger, polymorphism, cytoplasm, dna repair, transferase-dna-rna hybrid complex, transferase/dna-rna hybrid |
Biological source | Saccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast) More |
Cellular location | Nucleus: P04050 P08518 P16370 P20434 P20436 P27999 P38902 Nucleus, nucleolus: P40422 P22139 Cytoplasm: P20435 |
Total number of polymer chains | 13 |
Total formula weight | 486859.72 |
Authors | Wang, D.,Zhu, G.,Huang, X.,Lippard, S.J. (deposition date: 2010-03-10, release date: 2010-05-12, Last modification date: 2023-09-06) |
Primary citation | Wang, D.,Zhu, G.,Huang, X.,Lippard, S.J. X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc.Natl.Acad.Sci.USA, 107:9584-9589, 2010 Cited by PubMed: 20448203DOI: 10.1073/pnas.1002565107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.18 Å) |
Structure validation
Download full validation report