3M3Q

Crystal Structure of Agrocybe aegerita lectin AAL complexed with Ganglosides GM1 pentasaccharide

3M3Q の概要

• エントリーDOI: 10.2210/pdb3m3q/pdb
• 関連するPDBエントリー: 3AFK 3M3C 3M3E 3M3O
• 分子名称: Anti-tumor lectin, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: galectin, aal, ganglosides gm1, apoptosis, hydrolase, lectin, nuclease
• 由来する生物種: Agrocybe aegerita (Black poplar mushroom)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36215.76

構造登録者

Feng, L.,Li, D.,Wang, D. (登録日: 2010-03-09, 公開日: 2010-12-01, 最終更新日: 2023-11-01)

• 主引用文献: Feng, L.,Sun, H.,Zhang, Y.,Li, D.F.,Wang, D.C.; Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen; Faseb J., 24:3861-3868, 2010; PubMed: 20530247; DOI: 10.1096/fj.10-159111

実験手法

X-RAY DIFFRACTION (2.2 Å)