3M1S

Structure of Ruthenium Half-Sandwich Complex Bound to Glycogen Synthase Kinase 3

3M1S の概要

• エントリーDOI: 10.2210/pdb3m1s/pdb
• 分子名称: Glycogen synthase kinase-3 beta, Ruthenium pyridocarbazole (3 entities in total)
• 機能のキーワード: transferase, enzyme inhibitor, organometallic compound, ruthenium center, ruthenium pyridocarbazole, atp-binding, kinase, phosphoprotein, serine/threonine-protein kinase, wnt signaling pathway, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P49841
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 94595.30

構造登録者

Atilla-Gokcumen, G.E.,Di Costanzo, L.,Zimmermann, G.,Meggers, E. (登録日: 2010-03-05, 公開日: 2010-12-22, 最終更新日: 2023-09-06)

• 主引用文献: Atilla-Gokcumen, G.E.,Di Costanzo, L.,Meggers, E.; Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3beta; J.Biol.Inorg.Chem., 16:45-50, 2011; PubMed: 20821241; DOI: 10.1007/s00775-010-0699-x

実験手法

X-RAY DIFFRACTION (3.134 Å)