3M1B
Crystal structure of human FcRn with a dimeric peptide inhibitor
Summary for 3M1B
Entry DOI | 10.2210/pdb3m1b/pdb |
Related | 3M17 |
Related PRD ID | PRD_000816 |
Descriptor | IgG receptor FcRn large subunit p51, Beta-2-microglobulin, DIMERIC PEPTIDE INHIBITOR (3 entities in total) |
Functional Keywords | immunoglobulin binding protein, cell membrane, disulfide bond, glycoprotein, igg-binding protein, immunoglobulin domain, membrane, receptor, transmembrane, amyloid, amyloidosis, disease mutation, glycation, immune response, mhc i, pyrrolidone carboxylic acid, secreted, immune system-immune system inhibitor, immune system-inhibitor complex, immune system/inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein (By similarity): P55899 Secreted: P61769 |
Total number of polymer chains | 10 |
Total formula weight | 169212.22 |
Authors | Mezo, A.R.,Sridhar, V.,Badger, J.,Sakorafas, P.,Nienaber, V. (deposition date: 2010-03-04, release date: 2010-06-16, Last modification date: 2023-11-22) |
Primary citation | Mezo, A.R.,Sridhar, V.,Badger, J.,Sakorafas, P.,Nienaber, V. X-ray crystal structures of monomeric and dimeric peptide inhibitors in complex with the human neonatal Fc receptor, FcRn. J.Biol.Chem., 285:27694-27701, 2010 Cited by PubMed: 20592032DOI: 10.1074/jbc.M110.120667 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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