3LWM

Structure of the large fragment of thermus aquaticus DNA polymerase I in complex with a blunt-ended DNA and ddATP

3LWM の概要

• エントリーDOI: 10.2210/pdb3lwm/pdb
• 関連するPDBエントリー: 3KTQ 3LWL
• 分子名称: DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3'), DNA (5'-D(*TP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (9 entities in total)
• 機能のキーワード: dna replication, dna polymerases, dna-binding, dna-directed dna polymerase, amino acid-templating mechanism, nucleotidyltransferase, transferase, transferase-dna complex, blunt-ended dna, template-independent dna synthesis, terminal deoxynucleotidyl transferase, template-independent nucleotide addition, transferase/dna
• 由来する生物種: Thermus aquaticus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 69536.83

構造登録者

Marx, A.,Diederichs, K.,Obeid, S. (登録日: 2010-02-24, 公開日: 2010-05-05, 最終更新日: 2023-11-01)

• 主引用文献: Obeid, S.,Blatter, N.,Kranaster, R.,Schnur, A.,Diederichs, K.,Welte, W.,Marx, A.; Replication through an abasic DNA lesion: structural basis for adenine selectivity; Embo J., 29:1738-1747, 2010; PubMed: 20400942; DOI: 10.1038/emboj.2010.64

実験手法

X-RAY DIFFRACTION (2.186 Å)