3LTN
Inhibitor-stabilized topoisomerase IV-DNA cleavage complex (S. pneumoniae)
Summary for 3LTN
Entry DOI | 10.2210/pdb3ltn/pdb |
Related | 2NOV 3FOE 3FOF 3K9F 3KSA 3KSB |
Descriptor | DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, 5'-D(*AP*CP*CP*AP*AP*GP*GP*T*CP*AP*TP*GP*AP*AP*T)-3', ... (9 entities in total) |
Functional Keywords | topoisomerase, protein-dna cleavage complex, streptococcus pneumoniae, dna-binding, quinolone, dione, cleaved form, topoisomerase-dna complex, isomerase-dna complex, isomerase/dna |
Biological source | Streptococcus pneumoniae More |
Cellular location | Cell membrane; Peripheral membrane protein (By similarity): P72525 |
Total number of polymer chains | 8 |
Total formula weight | 195339.30 |
Authors | Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2010-02-16, release date: 2010-05-05, Last modification date: 2023-11-01) |
Primary citation | Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases Plos One, 5:e11338-e11338, 2010 Cited by PubMed: 20596531DOI: 10.1371/journal.pone.0011338 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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