3LSW

Aniracetam bound to the ligand binding domain of GluA3

Summary for 3LSW

• Entry DOI: 10.2210/pdb3lsw/pdb
• Related: 3LSF 3LSL 3LSX
• Descriptor: GluA2 S1S2 domain, GLUTAMIC ACID, 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE, ... (5 entities in total)
• Functional Keywords: glutamate receptor, glur3, glua3, ampa receptor, neurotransmitter receptor, s1s2, allosteric modulator, transport protein
• Biological source: Rattus norvegicus (Rat, Mouse); More
• Cellular location: Cell membrane ; Multi-pass membrane protein : Q9Z2W9
• Total number of polymer chains: 1
• Total formula weight: 29453.60

Authors

Ahmed, A.H.,Oswald, R.E. (deposition date: 2010-02-13, release date: 2010-03-16, Last modification date: 2023-09-06)

• Primary citation: Ahmed, A.H.,Oswald, R.E.; Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors.; J.Med.Chem., 53:2197-2203, 2010; PubMed: 20163115; DOI: 10.1021/jm901905j

Experimental method

X-RAY DIFFRACTION (1.752 Å)