3LS4
Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC
Summary for 3LS4
Entry DOI | 10.2210/pdb3ls4/pdb |
Related | 3LS5 |
Descriptor | Light chain of antibody Fab fragment, Heavy chain of antibody Fab fragment, (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol, ... (4 entities in total) |
Functional Keywords | immune system, antibody, immunoglobulin, fab fragment, cannabinoid complex |
Biological source | Mus musculus More |
Total number of polymer chains | 2 |
Total formula weight | 47032.73 |
Authors | Niemi, M.H.,Rouvinen, J. (deposition date: 2010-02-12, release date: 2010-06-02, Last modification date: 2024-04-03) |
Primary citation | Niemi, M.H.,Turunen, L.,Pulli, T.,Nevanen, T.K.,Hoyhtya, M.,Soderlund, H.,Rouvinen, J.,Takkinen, K. A structural insight into the molecular recognition of a (-)-Delta9-tetrahydrocannabinol and the development of a sensitive, one-step, homogeneous immunocomplex-based assay for its detection J.Mol.Biol., 400:803-814, 2010 Cited by PubMed: 20630472DOI: 10.1016/j.jmb.2010.05.048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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