3LRR
Crystal structure of human RIG-I CTD bound to a 12 bp AU rich 5' ppp dsRNA
Summary for 3LRR
Entry DOI | 10.2210/pdb3lrr/pdb |
Related | 3LRN |
Descriptor | Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(ATP)P*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*U)-3'), ZINC ION (3 entities in total) |
Functional Keywords | innate immunity, viral rna, rig-i like receptors, antiviral defense, atp-binding, helicase, hydrolase, immune response, metal-binding, nucleotide-binding, rna-binding, hydrolase-rna complex, hydrolase/rna |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: O95786 |
Total number of polymer chains | 4 |
Total formula weight | 36392.31 |
Authors | |
Primary citation | Lu, C.,Xu, H.,Ranjith-Kumar, C.T.,Brooks, M.T.,Hou, T.Y.,Hu, F.,Herr, A.B.,Strong, R.K.,Kao, C.C.,Li, P. The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain. Structure, 18:1032-1043, 2010 Cited by PubMed: 20637642DOI: 10.1016/j.str.2010.05.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
Download full validation report![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png)
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png)