3LQI
Crystal structure of MLL1 PHD3-Bromo complexed with H3(1-9)K4me2 peptide
Summary for 3LQI
Entry DOI | 10.2210/pdb3lqi/pdb |
Related | 3LQH 3LQJ |
Descriptor | MLL1 PHD3-Bromo, Histone H3, ZINC ION, ... (4 entities in total) |
Functional Keywords | phd finger, bromodomain, mll1, leukemia, h3(1-9)k4me2, chromosomal protein, dna-binding, nucleosome core, nucleus, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus . MLL cleavage product N320: Nucleus. MLL cleavage product C180: Nucleus: Q03164 Nucleus: P68431 |
Total number of polymer chains | 6 |
Total formula weight | 67579.23 |
Authors | Wang, Z.,Patel, D.J. (deposition date: 2010-02-09, release date: 2010-07-07, Last modification date: 2023-09-06) |
Primary citation | Wang, Z.,Song, J.,Milne, T.A.,Wang, G.G.,Li, H.,Allis, C.D.,Patel, D.J. Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell(Cambridge,Mass.), 141:1183-1194, 2010 Cited by PubMed: 20541251DOI: 10.1016/j.cell.2010.05.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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