3LQC
X-ray crystal structure of oxidized XRCC1 bound to DNA pol beta Palm thumb domain
Summary for 3LQC
Entry DOI | 10.2210/pdb3lqc/pdb |
Related | 3K75 3K77 |
Descriptor | DNA repair protein XRCC1, DNA polymerase beta, SODIUM ION, ... (5 entities in total) |
Functional Keywords | allosteric disulfide, scaffolding protein, dna repair, dna damage, nucleus, phosphoprotein, polymorphism, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, magnesium, metal-binding, nucleotidyltransferase, sodium, transferase, dna-binding protein, dna binding protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P18887 P06766 |
Total number of polymer chains | 2 |
Total formula weight | 44667.04 |
Authors | Cuneo, M.J.,Krahn, J.M.,London, R.E. (deposition date: 2010-02-09, release date: 2010-04-28, Last modification date: 2023-09-06) |
Primary citation | Cuneo, M.J.,London, R.E. Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Proc.Natl.Acad.Sci.USA, 107:6805-6810, 2010 Cited by PubMed: 20351257DOI: 10.1073/pnas.0914077107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.349 Å) |
Structure validation
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