3LQC

X-ray crystal structure of oxidized XRCC1 bound to DNA pol beta Palm thumb domain

3LQC の概要

• エントリーDOI: 10.2210/pdb3lqc/pdb
• 関連するPDBエントリー: 3K75 3K77
• 分子名称: DNA repair protein XRCC1, DNA polymerase beta, SODIUM ION, ... (5 entities in total)
• 機能のキーワード: allosteric disulfide, scaffolding protein, dna repair, dna damage, nucleus, phosphoprotein, polymorphism, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, magnesium, metal-binding, nucleotidyltransferase, sodium, transferase, dna-binding protein, dna binding protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: P18887 P06766
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44667.04

構造登録者

Cuneo, M.J.,Krahn, J.M.,London, R.E. (登録日: 2010-02-09, 公開日: 2010-04-28, 最終更新日: 2023-09-06)

• 主引用文献: Cuneo, M.J.,London, R.E.; Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.; Proc.Natl.Acad.Sci.USA, 107:6805-6810, 2010; PubMed: 20351257; DOI: 10.1073/pnas.0914077107

実験手法

X-RAY DIFFRACTION (2.349 Å)