3LO4

Crystal structure of human alpha-defensin 1 (R24A mutant)

Summary for 3LO4

Entry DOI	10.2210/pdb3lo4/pdb
Related	3GNY 3LO1 3LO2 3LO9 3LOE
Descriptor	Neutrophil defensin 1, DI(HYDROXYETHYL)ETHER, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	antimicrobial peptide, human alpha defensin 1, human neutrophil peptide 1, hnp1, antibiotic, antimicrobial, antiviral defense, defensin, disulfide bond, fungicide, phosphoprotein, secreted, antimicrobial protein
Cellular location	Secreted: P59665
Total number of polymer chains	2
Total formula weight	6979.68
Authors	Pazgier, M.,Lu, W. (deposition date: 2010-02-03, release date: 2010-03-09, Last modification date: 2023-09-06)
Primary citation	Wei, G.,Pazgier, M.,de Leeuw, E.,Rajabi, M.,Li, J.,Zou, G.,Jung, G.,Yuan, W.,Lu, W.Y.,Lehrer, R.I.,Lu, W. Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285:16275-16285, 2010 Cited by PubMed: 20220136 DOI: 10.1074/jbc.M110.102749 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation