3LNY

Second PDZ domain from human PTP1E in complex with RA-GEF2 peptide

3LNY の概要

• エントリーDOI: 10.2210/pdb3lny/pdb
• 分子名称: Tyrosine-protein phosphatase non-receptor type 13, Rap guanine nucleotide exchange factor 6, THIOCYANATE ION, ... (5 entities in total)
• 機能のキーワード: pdz2, structural genomics, protein structure initiative, psi-2, center for eukaryotic structural genomics, cesg, cytoskeleton, cell membrane, guanine-nucleotide releasing factor, signaling protein-signaling protein complex, signaling protein/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton : Q12923; Cytoplasm : Q8TEU7
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 10902.14

構造登録者

Zhang, J.,Chang, A.,Ke, H.,Phillips Jr., G.N.,Lee, A.L.,Center for Eukaryotic Structural Genomics (CESG) (登録日: 2010-02-03, 公開日: 2010-03-23, 最終更新日: 2024-02-21)

• 主引用文献: Zhang, J.,Sapienza, P.J.,Ke, H.,Chang, A.,Hengel, S.R.,Wang, H.,Phillips, G.N.,Lee, A.L.; Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.; Biochemistry, 49:9280-9291, 2010; PubMed: 20839809; DOI: 10.1021/bi101131f

実験手法

X-RAY DIFFRACTION (1.3 Å)