3LJU
Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3
Summary for 3LJU
Entry DOI | 10.2210/pdb3lju/pdb |
Descriptor | Arf-GAP with dual PH domain-containing protein 1, ZINC ION, (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, ... (4 entities in total) |
Functional Keywords | structural genomics consortium, gap, gtpase activation, sgc, metal-binding, nucleus, phosphoprotein, zinc-finger, hydrolase activator |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O75689 |
Total number of polymer chains | 1 |
Total formula weight | 46718.28 |
Authors | Shen, L.,Tong, Y.,Tempel, W.,MacKenzie, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2010-01-26, release date: 2010-11-24, Last modification date: 2023-09-06) |
Primary citation | Tong, Y.,Tempel, W.,Wang, H.,Yamada, K.,Shen, L.,Senisterra, G.A.,MacKenzie, F.,Chishti, A.H.,Park, H.W. Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1. Proc.Natl.Acad.Sci.USA, 107:20346-20351, 2010 Cited by PubMed: 21057110DOI: 10.1073/pnas.1009008107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.702 Å) |
Structure validation
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