3LI2

Closed Conformation of HtsA Complexed with Staphyloferrin A

Summary for 3LI2

• Entry DOI: 10.2210/pdb3li2/pdb
• Related: 3LHS 3eiw 3eix
• Descriptor: Ferrichrome ABC transporter lipoprotein, FE (III) ION, (2R)-2-(2-{[(1R)-1-carboxy-4-{[(3S)-3,4-dicarboxy-3-hydroxybutanoyl]amino}butyl]amino}-2-oxoethyl)-2-hydroxybutanedioic acid, ... (6 entities in total)
• Functional Keywords: siderophore, iron, receptor, lipoprotein, binding protein, transport protein
• Biological source: Staphylococcus aureus subsp. aureus
• Total number of polymer chains: 2
• Total formula weight: 68111.91

Authors

Grigg, J.C.,Murphy, M.E.P. (deposition date: 2010-01-23, release date: 2010-02-09, Last modification date: 2024-02-21)

• Primary citation: Grigg, J.C.,Cooper, J.D.,Cheung, J.,Heinrichs, D.E.,Murphy, M.E.; The Staphylococcus aureus siderophore receptor HtsA undergoes localized conformational changes to enclose staphyloferrin A in an arginine-rich binding pocket.; J.Biol.Chem., 285:11162-11171, 2010; PubMed: 20147287; DOI: 10.1074/jbc.M109.097865

Experimental method

X-RAY DIFFRACTION (2.2 Å)