3LDX

Discovery and Clinical Evaluation of RWJ-671818, a Thrombin Inhibitor with an Oxyguanidine P1 Motif

Summary for 3LDX

• Entry DOI: 10.2210/pdb3ldx/pdb
• Descriptor: Thrombin light chain, Thrombin heavy chain, Hirudin variant-1, ... (5 entities in total)
• Functional Keywords: blood clotting, hydrolase-hydrolase inhibitor complex, blood coagulation, serine protease, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734 P00734; Secreted: P01050
• Total number of polymer chains: 3
• Total formula weight: 35711.63

Authors

Spurlino, J.C. (deposition date: 2010-01-13, release date: 2011-08-10, Last modification date: 2024-11-27)

• Primary citation: Spurlino, J.C.; Discovery and Clinical Evaluation of RWJ-671818, a Thrombin Inhibitor with an Oxyguanidine P1 Motif; To be Published,

Experimental method

X-RAY DIFFRACTION (2.246 Å)