3LDX

Discovery and Clinical Evaluation of RWJ-671818, a Thrombin Inhibitor with an Oxyguanidine P1 Motif

3LDX の概要

• エントリーDOI: 10.2210/pdb3ldx/pdb
• 分子名称: Thrombin light chain, Thrombin heavy chain, Hirudin variant-1, ... (5 entities in total)
• 機能のキーワード: blood clotting, hydrolase-hydrolase inhibitor complex, blood coagulation, serine protease, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P00734; Secreted: P01050
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 35711.63

構造登録者

Spurlino, J.C. (登録日: 2010-01-13, 公開日: 2011-08-10, 最終更新日: 2024-11-27)

• 主引用文献: Spurlino, J.C.; Discovery and Clinical Evaluation of RWJ-671818, a Thrombin Inhibitor with an Oxyguanidine P1 Motif; To be Published,

実験手法

X-RAY DIFFRACTION (2.246 Å)