3LD1

Crystal Structure of IBV Nsp2a

Summary for 3LD1

DescriptorReplicase polyprotein 1a (2 entities in total)
Functional Keywordsglobular like, host cytoplasm, host membrane, membrane, metal-binding, protease, rna-binding, thiol protease, transmembrane, zinc-finger, hydrolase
Biological sourceAvian infectious bronchitis virus (strain M41) (IBV)
Cellular locationNon-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region  P0C6V5
Total number of polymer chains1
Total molecular weight39757.32
Authors
Xu, Y.,Cong, L.,Wei, L.,Fu, J.,Chen, C.,Yang, A.,Tang, H.,Bartlam, M.,Rao, Z. (deposition date: 2010-01-12, release date: 2011-05-25, Last modification date: 2017-11-01)
Primary citation
Xu, Y.,Ye, Z.,Wei, L.,Cong, L.,Fu, J.,Chen, C.,Yang, A.,Wu, W.,Tang, H.,Bartlam, M.,Rao, Z.
IBV nsp2 is an endosome-associated protein and viral pathogenicity factor
To be Published,
Experimental method
X-RAY DIFFRACTION (2.498 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.272202.2%11.8%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution