3LA6

Octameric kinase domain of the E. coli tyrosine kinase Wzc with bound ADP

3LA6 の概要

• エントリーDOI: 10.2210/pdb3la6/pdb
• 分子名称: Tyrosine-protein kinase wzc, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION (3 entities in total)
• 機能のキーワード: p-loop protein, nucleotide binding domain, walker a motif, bacterial protein kinase, oligomerization, intermolecular phosphorylation, exopolysaccharide synthesis, transferase
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cell inner membrane; Multi-pass membrane protein: P76387
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 514360.72

構造登録者

Gruszczyk, J.,Nessler, S.,Gueguen-Chaignon, V.,Vigouroux, A.,Bechet, E.,Grangeasse, C. (登録日: 2010-01-06, 公開日: 2010-08-25, 最終更新日: 2023-11-01)

• 主引用文献: Bechet, E.,Gruszczyk, J.,Terreux, R.,Gueguen-Chaignon, V.,Vigouroux, A.,Obadia, B.,Cozzone, A.J.,Nessler, S.,Grangeasse, C.; Identification of structural and molecular determinants of the tyrosine-kinase Wzc and implications in capsular polysaccharide export; Mol.Microbiol., 77:1315-1325, 2010; PubMed: 20633230; DOI: 10.1111/j.1365-2958.2010.07291.x

実験手法

X-RAY DIFFRACTION (3.2 Å)