3L3X

Crystal structure of DHT-bound androgen receptor in complex with the first motif of steroid receptor coactivator 3

Summary for 3L3X

• Entry DOI: 10.2210/pdb3l3x/pdb
• Related: 3L3Z
• Descriptor: Androgen receptor, Nuclear receptor coactivator 3, 5-ALPHA-DIHYDROTESTOSTERONE, ... (4 entities in total)
• Functional Keywords: androgen receptor, ligand binding domain, steroid receptor coactivator 3, 5-alpha-dihydrotestosterone (dht), prostate cancer, protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : P10275; Cytoplasm: Q9Y6Q9
• Total number of polymer chains: 2
• Total formula weight: 30797.27

Authors

Zhou, X.E.,Suino-Powell, K.M.,Li, J.,He, A.,MacKeigan, J.P.,Melcher, K.,Yong, E.-L.,Xu, H.E. (deposition date: 2009-12-18, release date: 2010-01-12, Last modification date: 2017-11-01)

• Primary citation: Zhou, X.E.,Suino-Powell, K.M.,Li, J.,He, Y.,Mackeigan, J.P.,Melcher, K.,Yong, E.L.,Xu, H.E.; Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor.; J.Biol.Chem., 285:9161-9171, 2010; PubMed: 20086010; DOI: 10.1074/jbc.M109.085779

Experimental method

X-RAY DIFFRACTION (1.55 Å)