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3L3V

Structure of HIV-1 integrase core domain in complex with sucrose

Summary for 3L3V
Entry DOI10.2210/pdb3l3v/pdb
Related1BL3 1EXQ 3L3U
Related PRD IDPRD_900003
DescriptorPOL polyprotein, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, SULFATE ION, ... (5 entities in total)
Functional Keywordsdna integration, aids, integrase, endonuclease, polynucleotidyl transferase, dna binding, viral protein
Biological sourceHuman immunodeficiency virus 1
Total number of polymer chains2
Total formula weight36588.41
Authors
Wielens, J.,Chalmers, D.K.,Scanlon, M.J.,Parker, M.W. (deposition date: 2009-12-18, release date: 2010-03-31, Last modification date: 2023-11-01)
Primary citationWielens, J.,Headey, S.J.,Jeevarajah, D.,Rhodes, D.I.,Deadman, J.,Chalmers, D.K.,Scanlon, M.J.,Parker, M.W.
Crystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site
Febs Lett., 584:1455-1462, 2010
Cited by
PubMed: 20227411
DOI: 10.1016/j.febslet.2010.03.016
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

217705

数据于2024-03-27公开中

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