3L3J

Crystal structure of HLA-B*4402 in complex with the F3A/R5A double mutant of a self-peptide derived from DPA*0201

3L3J の概要

• エントリーDOI: 10.2210/pdb3l3j/pdb
• 関連するPDBエントリー: 1M6O 3L3D 3L3G 3L3I 3L3K
• 分子名称: HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, peptide from HLA-DPA1 protein, ... (5 entities in total)
• 機能のキーワード: immunoglobulin domain, immune response, major histocompatibility complex class i, mhc-i peptide complex, altered peptide ligand, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P30481; Secreted: P61769
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44715.42

構造登録者

Theodossis, A.,Ely, L.K.,Rossjohn, J. (登録日: 2009-12-17, 公開日: 2010-03-16, 最終更新日: 2023-11-01)

• 主引用文献: Theodossis, A.,Guillonneau, C.,Welland, A.,Ely, L.K.,Clements, C.S.,Williamson, N.A.,Webb, A.I.,Wilce, J.A.,Mulder, R.J.,Dunstone, M.A.,Doherty, P.C.,McCluskey, J.,Purcell, A.W.,Turner, S.J.,Rossjohn, J.; Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition; Proc.Natl.Acad.Sci.USA, 107:5534-5539, 2010; PubMed: 20212169; DOI: 10.1073/pnas.1000032107

実験手法

X-RAY DIFFRACTION (2.4 Å)