3L1F
Bovine AlphaA crystallin
Summary for 3L1F
Entry DOI | 10.2210/pdb3l1f/pdb |
Descriptor | Alpha-crystallin A chain, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total) |
Functional Keywords | lens transparency, polydispersity, protein aggregation, crystallin, eye lens protein, chaperone |
Biological source | Bos taurus (bovine) |
Cellular location | Cytoplasm : P02470 |
Total number of polymer chains | 1 |
Total formula weight | 11777.09 |
Authors | Laganowsky, A.,Sawaya, M.R.,Cascio, D.,Eisenberg, D. (deposition date: 2009-12-11, release date: 2010-05-12, Last modification date: 2024-02-21) |
Primary citation | Laganowsky, A.,Benesch, J.L.,Landau, M.,Ding, L.,Sawaya, M.R.,Cascio, D.,Huang, Q.,Robinson, C.V.,Horwitz, J.,Eisenberg, D. Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci., 19:1031-1043, 2010 Cited by PubMed: 20440841DOI: 10.1002/pro.380 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
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