3L14

Human Carbonic Anhydrase II complexed with Althiazide

Summary for 3L14

• Entry DOI: 10.2210/pdb3l14/pdb
• Descriptor: Carbonic anhydrase 2, ZINC ION, 4-AMINO-6-CHLOROBENZENE-1,3-DISULFONAMIDE, ... (4 entities in total)
• Functional Keywords: lyase, carbonic anhydrase ii, althiazide, 6-chloro-3, 4-dihydro-3-((2-propenylthio)methyl)-2h-1, 2, 4-benzothiadiazine-7-sulfonamide, disease mutation, metal-binding
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00918
• Total number of polymer chains: 1
• Total formula weight: 29640.20

Authors

Quirit, J.G.,Robbins, A.,Genis, C.,Tu, C.,Silverman, D.N.,McKenna, R. (deposition date: 2009-12-10, release date: 2011-01-05, Last modification date: 2024-02-21)

• Primary citation: Quirit, J.G.,Robbins, A.,Rocca, J.R.,Johnson, J.,Genis, C.,Tu, C.,Silverman, D.N.,McKenna, R.; The Promiscuous Nature of Althiazide in Adducts with CA II and CA IX Mimic; To be Published,

Experimental method

X-RAY DIFFRACTION (1.22 Å)