3L14

Human Carbonic Anhydrase II complexed with Althiazide

3L14 の概要

分子名称Carbonic anhydrase 2, ZINC ION, 4-AMINO-6-CHLOROBENZENE-1,3-DISULFONAMIDE, ... (4 entities in total)
機能のキーワード2, lyase, carbonic anhydrase ii, althiazide, 6-chloro-3, 4-dihydro-3-((2-propenylthio)methyl)-2h-1, 4-benzothiadiazine-7-sulfonamide, disease mutation, metal-binding
由来する生物種Homo sapiens (human)
細胞内の位置Cytoplasm P00918
ポリマー鎖数1
分子量合計29640.2
構造登録者
Quirit, J.G.,Robbins, A.,Genis, C.,Tu, C.,Silverman, D.N.,McKenna, R. (登録日: 2009-12-10, 公開日: 2011-01-05, 最終更新日: 2011-07-13)
主引用文献
Quirit, J.G.,Robbins, A.,Rocca, J.R.,Johnson, J.,Genis, C.,Tu, C.,Silverman, D.N.,McKenna, R.
The Promiscuous Nature of Althiazide in Adducts with CA II and CA IX Mimic
To be Published,
実験手法
X-RAY DIFFRACTION (1.22 Å)
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構造検証レポート

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers602.3%6.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード