3KZ0
MCL-1 complex with MCL-1-specific selected peptide
Summary for 3KZ0
Entry DOI | 10.2210/pdb3kz0/pdb |
Descriptor | Induced myeloid leukemia cell differentiation protein Mcl-1, Mcl-1 specific peptide MB7, ZINC ION, ... (5 entities in total) |
Functional Keywords | bcl-2, bh3, mitochondrion, apoptosis, anti-apoptotic |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane ; Single-pass membrane protein : Q07820 |
Total number of polymer chains | 4 |
Total formula weight | 42020.77 |
Authors | Dutta, S.,Fire, E.,Grant, R.A.,Sauer, R.T.,Keating, A.E. (deposition date: 2009-12-07, release date: 2010-05-05, Last modification date: 2023-09-06) |
Primary citation | Dutta, S.,Gulla, S.,Chen, T.S.,Fire, E.,Grant, R.A.,Keating, A.E. Determinants of BH3 binding specificity for Mcl-1 versus Bcl-xL. J.Mol.Biol., 398:747-762, 2010 Cited by PubMed: 20363230DOI: 10.1016/j.jmb.2010.03.058 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.349 Å) |
Structure validation
Download full validation report