3KYL
Structure of the catalytic subunit of telomerase bound to its RNA template and telomeric DNA
Summary for 3KYL
Entry DOI | 10.2210/pdb3kyl/pdb |
Descriptor | Telomerase reverse transcriptase, DNA/RNA (5'-R(*CP*UP*GP*AP*CP*CP*UP*GP*AP*C)-D(P*TP*TP*CP*GP*GP*TP*CP*AP*GP*GP*TP*CP*AP*G)-3'), MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | reverse transcriptase, protein-rna-dna complex, telomerase, rna-directed dna polymerase, nucleic acid binding protein-dna-rna complex, nucleic acid binding protein/dna/rna |
Biological source | Tribolium castaneum (rust-red flour beetle) |
Total number of polymer chains | 2 |
Total formula weight | 78106.71 |
Authors | Skordalakes, E. (deposition date: 2009-12-06, release date: 2010-03-31, Last modification date: 2024-02-21) |
Primary citation | Mitchell, M.,Gillis, A.,Futahashi, M.,Fujiwara, H.,Skordalakes, E. Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA. Nat.Struct.Mol.Biol., 17:513-518, 2010 Cited by PubMed: 20357774DOI: 10.1038/nsmb.1777 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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