3KXX
Structure of the mutant Fibroblast Growth Factor receptor 1
Summary for 3KXX
| Entry DOI | 10.2210/pdb3kxx/pdb |
| Related | 3KY2 |
| Descriptor | Basic fibroblast growth factor receptor 1 (1 entity in total) |
| Functional Keywords | kinase, rtk, interface, phosphorylation, alternative splicing, atp-binding, chromosomal rearrangement, craniosynostosis, disease mutation, disulfide bond, dwarfism, glycoprotein, heparin-binding, hypogonadotropic hypogonadism, immunoglobulin domain, kallmann syndrome, membrane, nucleotide-binding, phosphoprotein, polymorphism, receptor, transferase, transmembrane, tyrosine-protein kinase |
| Biological source | Homo sapiens (human) |
| Cellular location | Membrane; Single-pass type I membrane protein: P11362 |
| Total number of polymer chains | 4 |
| Total formula weight | 144794.09 |
| Authors | Bae, J.H.,Boggon, T.J.,Tome, F.,Mandiyan, V.,Lax, I.,Schlessinger, J. (deposition date: 2009-12-04, release date: 2010-03-02, Last modification date: 2023-09-06) |
| Primary citation | Bae, J.H.,Boggon, T.J.,Tome, F.,Mandiyan, V.,Lax, I.,Schlessinger, J. Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells. Proc.Natl.Acad.Sci.USA, 107:2866-2871, 2010 Cited by PubMed: 20133753DOI: 10.1073/pnas.0914157107 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
Download full validation report
