3KXH

Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor (2-dymethylammino-4,5,6,7-tetrabromobenzoimidazol-1yl-acetic acid (K66)

3KXH の概要

• エントリーDOI: 10.2210/pdb3kxh/pdb
• 関連するPDBエントリー: 1zoh 2oxx 3KXG 3KXJ 3KXM 3KXN
• 分子名称: Casein kinase II subunit alpha, [4,5,6,7-tetrabromo-2-(dimethylamino)-1H-benzimidazol-1-yl]acetic acid, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• 機能のキーワード: protein kinase ck2-inhibitor complex, atp-binding, kinase, nucleotide-binding, serine/threonine-protein kinase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Zea mays (maize)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39330.34

構造登録者

Papinutto, E.,Franchin, C.,Battistutta, R. (登録日: 2009-12-03, 公開日: 2010-11-17, 最終更新日: 2017-11-01)

• 主引用文献: Sarno, S.,Papinutto, E.,Franchin, C.,Bain, J.,Elliott, M.,Meggio, F.,Kazimierczuk, Z.,Orzeszko, A.,Zanotti, G.,Battistutta, R.,Pinna, L.A.; ATP site-directed inhibitors of protein kinase CK2: an update.; Curr Top Med Chem, 11:1340-1351, 2011; PubMed: 21513497

実験手法

X-RAY DIFFRACTION (1.7 Å)