3KW7

Crystal structure of LacB from Trametes sp. AH28-2

3KW7 の概要

• エントリーDOI: 10.2210/pdb3kw7/pdb
• 分子名称: Laccase B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... (5 entities in total)
• 機能のキーワード: laccase, metal-binding, oxidoreductase
• 由来する生物種: Trametes
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 110885.37

構造登録者

Ge, H.H.,Teng, M.K.,Niu, L.W. (登録日: 2009-12-01, 公開日: 2010-03-09, 最終更新日: 2024-10-09)

主引用文献

Ge, H.H.,Gao, Y.X.,Hong, Y.Z.,Zhang, M.,Xiao, Y.Z.,Teng, M.K.,Niu, L.W.
Structure of native laccase B from Trametes sp. AH28-2
Acta Crystallogr.,Sect.F, 66:254-258, 2010

PubMed Abstract: Fungal laccases are oxidoreductases that belong to the multinuclear copper-containing oxidases. They are able to oxidize a wide range of substrates, preferably phenolic compounds, which makes them suitable for employment in the bioremediation of soil and water as well as in other biotechnological applications. Here, the structural analysis of natural laccase B (LacB) from Trametes sp. AH28-2 is presented. This structure provides the opportunity to study the natural post-translational modifications of the enzyme. The overall fold shows a high homology to those of previously analyzed laccases with known three-dimensional structure. However, LacB contains a new structural element, a protruding loop near the substrate-binding site, compared with the previously reported laccase structures. This unique structural feature may be involved in modulation of the substrate recognition of LacB.

PubMed: 20208154
DOI: 10.1107/S1744309110000084

実験手法

X-RAY DIFFRACTION (3.44 Å)