3KVV

Trapping of an oxocarbenium ion intermediate in UP crystals

Summary for 3KVV

Entry DOI	10.2210/pdb3kvv/pdb
Related	3KU4 3KUK 3KVR 3KVY
Descriptor	Uridine phosphorylase, 5-FLUOROURACIL, SULFATE ION, ... (5 entities in total)
Functional Keywords	oxocarbenium ion, glycal, pyrimidine salvage, uridine phosphorylase, cytoplasm, glycosyltransferase, transferase
Biological source	Escherichia coli
Total number of polymer chains	6
Total formula weight	165283.86
Authors	Paul, D.,O'Leary, S.,Rajashankar, K.,Bu, W.,Toms, A.,Settembre, E.,Sanders, J.,Begley, T.P.,Ealick, S.E. (deposition date: 2009-11-30, release date: 2010-04-28, Last modification date: 2024-02-21)
Primary citation	Paul, D.,O'Leary, S.E.,Rajashankar, K.,Bu, W.,Toms, A.,Settembre, E.C.,Sanders, J.M.,Begley, T.P.,Ealick, S.E. Glycal formation in crystals of uridine phosphorylase. Biochemistry, 49:3499-3509, 2010 Cited by PubMed: 20364833 DOI: 10.1021/bi902073b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation