3KUV

Structural basis of the activity and substrate specificity of the fluoroacetyl-CoA thioesterase FlK - T42S mutant in complex with acetate.

Summary for 3KUV

• Entry DOI: 10.2210/pdb3kuv/pdb
• Related: 3KUW 3KV7 3KV8 3KVI 3KVU 3KVZ 3KW1 3KX7 3KX8
• Descriptor: Fluoroacetyl coenzyme A thioesterase, ACETATE ION (3 entities in total)
• Functional Keywords: fluoroacetyl-coa thioesterase flk, hot dog folding, thioesterase, hydrolase
• Biological source: Streptomyces cattleya
• Total number of polymer chains: 2
• Total formula weight: 30944.13

Authors

Dias, M.V.B.,Huang, F.,Chirgadze, D.Y.,Tosin, M.,Spiteller, D.,Valentine, E.F.,Leadlay, P.F.,Spencer, J.B.,Blundell, T.L. (deposition date: 2009-11-27, release date: 2010-04-21, Last modification date: 2023-09-06)

• Primary citation: Dias, M.V.,Huang, F.,Chirgadze, D.Y.,Tosin, M.,Spiteller, D.,Dry, E.F.,Leadlay, P.F.,Spencer, J.B.,Blundell, T.L.; Structural basis for the activity and substrate specificity of fluoroacetyl-CoA thioesterase FlK.; J.Biol.Chem., 285:22495-22504, 2010; PubMed: 20430898; DOI: 10.1074/jbc.M110.107177

Experimental method

X-RAY DIFFRACTION (1.5 Å)