3KT0

Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase

3KT0 の概要

• エントリーDOI: 10.2210/pdb3kt0/pdb
• 関連するPDBエントリー: 3KT3 3KT6 3KT8
• 分子名称: Tryptophanyl-tRNA synthetase, cytoplasmic, (2S)-1-{[(2S)-3-(2-methoxyethoxy)-2-methylpropyl]oxy}propan-2-amine (3 entities in total)
• 機能のキーワード: tryptophanyl-trna synthetase, rossmann fold, s. cerevisiae, aminoacyl-trna synthetase, atp-binding, cytoplasm, ligase, nucleotide-binding, protein biosynthesis
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast)
• 細胞内の位置: Cytoplasm: Q12109
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 50453.39

構造登録者

Zhou, M.,Dong, X.,Zhong, C.,Shen, N.,Ding, J. (登録日: 2009-11-24, 公開日: 2010-02-16, 最終更新日: 2023-11-01)

• 主引用文献: Zhou, M.,Dong, X.,Shen, N.,Zhong, C.,Ding, J.; Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design; Nucleic Acids Res., 38:3399-3413, 2010; PubMed: 20123733; DOI: 10.1093/nar/gkp1254

実験手法

X-RAY DIFFRACTION (2.1 Å)