3KPZ
Crystal structure of a novel vitamin D3 analogue, ZK203278 showing dissociated profile
Summary for 3KPZ
| Entry DOI | 10.2210/pdb3kpz/pdb |
| Related | 1DB1 1IE8 1IE9 |
| Descriptor | Vitamin D3 receptor, (1R,3S,5Z)-5-[(2E)-2-{(1R,3aS,7aR)-1-[(1R,5S)-5-hydroxy-1-methyl-5-(1,3-thiazol-2-yl)pentyl]-7a-methyloctahydro-4H-inden-4-ylidene}ethylidene]-4-methylidenecyclohexane-1,3-diol (3 entities in total) |
| Functional Keywords | nuclear receptor, agonist, dna-binding, transcription regulation, transcription-hormone complex, transcription/hormone |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus: P11473 |
| Total number of polymer chains | 1 |
| Total formula weight | 29863.57 |
| Authors | Rochel, N.,Moras, D. (deposition date: 2009-11-17, release date: 2011-10-12, Last modification date: 2023-09-06) |
| Primary citation | Rochel, N.,Moras, D. Crystal structure of a vitamin D3 analog, ZK203278, showing dissociated profile. Anticancer Res., 32:335-339, 2012 Cited by PubMed: 22213324PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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