3KPR
Crystal Structure of the LC13 TCR in complex with HLA B*4405 bound to EEYLKAWTF a mimotope
Summary for 3KPR
Entry DOI | 10.2210/pdb3kpr/pdb |
Related | 3KPL 3KPM 3KPN 3KPO 3KPP 3KPQ 3KPS |
Descriptor | HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ... (6 entities in total) |
Functional Keywords | hla b*4405, tcrpmhc structure, ternary complex, allorecognition, tcr recognition, self peptide, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, polymorphism, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P30481 Secreted . Note=(Microbial infection) In the presence of M: P61769 |
Total number of polymer chains | 10 |
Total formula weight | 188869.16 |
Authors | Macdonald, W.A.,Chen, Z.,Gras, S.,Archbold, J.K.,Tynan, F.E.,Clements, C.S.,Bharadwaj, M.,Kjer-Nielsen, L.,Saunders, P.M.,Wilce, M.C.,Crawford, F.,Stadinsky, B.,Jackson, D.,Brooks, A.G.,Purcell, A.W.,Kappler, J.W.,Burrows, S.R.,Rossjohn, J.,McCluskey, J. (deposition date: 2009-11-16, release date: 2009-12-22, Last modification date: 2023-09-06) |
Primary citation | Macdonald, W.A.,Chen, Z.,Gras, S.,Archbold, J.K.,Tynan, F.E.,Clements, C.S.,Bharadwaj, M.,Kjer-Nielsen, L.,Saunders, P.M.,Wilce, M.C.,Crawford, F.,Stadinsky, B.,Jackson, D.,Brooks, A.G.,Purcell, A.W.,Kappler, J.W.,Burrows, S.R.,Rossjohn, J.,McCluskey, J. T cell allorecognition via molecular mimicry. Immunity, 31:897-908, 2009 Cited by PubMed: 20064448DOI: 10.1016/j.immuni.2009.09.025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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