3KPM

Crystal Structure of HLA B*4402 in complex with EEYLKAWTF, a mimotope

3KPM の概要

• エントリーDOI: 10.2210/pdb3kpm/pdb
• 関連するPDBエントリー: 3KPL 3KPN 3KPO 3KPP 3KPQ 3KPR 3KPS
• 分子名称: HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ... (4 entities in total)
• 機能のキーワード: hla b*4402, allorecognition, tcr recognition, mimotope peptide, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, transmembrane, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P30481; Secreted . Note=(Microbial infection) In the presence of M: P61769
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44915.74

構造登録者

Macdonald, W.A.,Chen, Z.,Gras, S.,Archbold, J.K.,Tynan, F.E.,Clements, C.S.,Bharadwaj, M.,Kjer-Nielsen, L.,Saunders, P.M.,Wilce, M.C.,Crawford, F.,Stadinsky, B.,Jackson, D.,Brooks, A.G.,Purcell, A.W.,Kappler, J.W.,Burrows, S.R.,Rossjohn, J.,McCluskey, J. (登録日: 2009-11-16, 公開日: 2009-12-22, 最終更新日: 2023-09-06)

• 主引用文献: Macdonald, W.A.,Chen, Z.,Gras, S.,Archbold, J.K.,Tynan, F.E.,Clements, C.S.,Bharadwaj, M.,Kjer-Nielsen, L.,Saunders, P.M.,Wilce, M.C.,Crawford, F.,Stadinsky, B.,Jackson, D.,Brooks, A.G.,Purcell, A.W.,Kappler, J.W.,Burrows, S.R.,Rossjohn, J.,McCluskey, J.; T cell allorecognition via molecular mimicry.; Immunity, 31:897-908, 2009; PubMed: 20064448; DOI: 10.1016/j.immuni.2009.09.025

実験手法

X-RAY DIFFRACTION (1.6 Å)